Thienopyrrole-expanded BODIPY as a potential NIR photosensitizer for photodynamic therapy.
نویسندگان
چکیده
The synthesis and characterization of a highly photostable bromo-substituted BODIPY dye (I) fused-ring-expanded with thienopyrrole moieties is reported. The results of MTT assays and flow cytometric analyses in living HeLa cells demonstrate that I has a high singlet oxygen quantum yield (ΦΔ = 0.63) and exhibits photocytotoxicity upon irradiation in the NIR region making it potentially suitable for use in PDT.
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عنوان ژورنال:
- Chemical communications
دوره 49 38 شماره
صفحات -
تاریخ انتشار 2013